Aminosalicylates
Sulfasalazine
CBC and CMP
-baseline
-Q2w x 6, then Qm x 3, then Q6m
UA and urinary quantitative microalbumin (morning well-hydrated spot urine specimen)
-baseline
-Qm x 3, then Q3m x 4, then Q6m
Mesalamine and other 5-ASA agents
CBC and CMP
-baseline
-q12m
UA and Urinary quantitative microalbumin (morning well-hydrated urine spot urine specimen)
-baseline
-Qm x 3, then Q3m x 4, then Q6m
Thiopurines and Other Anti-metabolites
6-mercaptopurine and azathioprine
EBV serology (in young EBV-seronegative patients risk of fatal post-mononucleosis myeloproliferation of 3/1000 in males; risk of fatal hemophagocytic lymphohistiocytosis after primary EBV infection in both genders)
-baseline
Varicella serology
PROMETHEUS® TPMT Enzyme - #3320
-baseline
CBC
-baseline
-q1w x 2, then q2w x 2, then q4w x 2, then q2-3m
CMP
-with every other CBC
PROMETHEUS® Thiopurine Metabolites - #3200 Thiopurine metabolite (6-TGN, 6-MMPN) levels
-as directed by attending physician
Dermatologic examination for nonmelanoma skin cancer
-as directed by attending physician
Methotrexate (SC, given weekly at induction dose of 25 mg/w for 3m, then maintenance of 15 mg/w; supplemental oral folate 1 mg/d)
CBC, CMP
-baseline
-monthly
Dermatologic examination for nonmelanoma skin cancer
-as directed by attending physician
Corticosteroids
Budesonide
BP and blood glucose
-quarterly
Ophthalmology examination
-annually
DEXA
-baseline
-annually (if stable after 2 annual evaluations, decrease frequency or suspend)
TNF-inhibitors
Baseline
Vaccination history
Chest x-ray PA and lateral
PPD with controls or QuantiFERON TB Gold In Tube
Hepatitis B Virus Surface Antibody 0020090
Hepatitis B Virus Surface Antigen with Reflex to Confirmation 0020089
Review of Figure 1 (Anti-TNF-Alpha Agents Pre-Order Checklist) in the paper linked at the bottom of this section is recommended.
Quarterly
-CBC, CMP
Annually
Pap smear
Dermatologic examination for nonmelanoma skin cancer
-as directed by attending physician
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